BackgroundMetagenomic next-generation sequencing (mNGS) is a promising technology that allows unbiased pathogen detection and is increasingly being used for clinical diagnoses.However, its application in urinary tract infection (UTI) is still scarce.MethodsThe medical records of 33 patients oliver peoples forman r with suspected UTI who were admitt
Abstract Background Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in the liver parenchyma and tissue remodelling.Different cell types of the liver are known to play distinct roles in liver injury response.Hepatocytes and liver endothelial cells receive mo
Abstract This study assesses the neuroprotective potential of CPP-P1, a conjugate of an anti-apoptotic peptain-1 (P1) and a cell-penetrating peptide (CPP) in in vitro, in vivo, and ex vivo glaucoma models.Primary retinal ganglion cells (RGCs) were subjected to either neurotrophic factor (NF) deprivation for 48 h or endothelin-3 (ET-3) treatment for
oliver peoples forman r An adequate method for calculating chemical equilibrium in a predominantly gaseous, multi-component reactive mixture was investigated and successfully applied.This method involves the stated equilibrium reaction scheme, including, first, the formation of chemical species, of which concentrations prevail in the mixture, then